LAIR2 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All LAIR2 reagents are produced in house and quality controlled, including 4 LAIR2 Antibody, 2 LAIR2 ELISA, 13 LAIR2 Gene, 3 LAIR2 Lysate, 3 LAIR2 Protein, 1 LAIR2 qPCR. All LAIR2 reagents are ready to use.

LAIR2 Protein (3)

    LAIR2 Antibody (4)

      LAIR2 ELISA Kit & Match Antibody ELISA Pair Set (2)

      LAIR2 cDNA Clone (13)

      NM_002288.3

      LAIR2 qPCR Primer (1)

      LAIR2 Lysate (3)

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        LAIR2 Background

        Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

        LAIR2 References

        • Meyaard, L. et al.,1997, Immunity.7:283-290.
        • Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
        • Meyaard, L. et al., 2001,  J. Exp. Med. 194 (1): 107-112.
        • Meyaard, L., 2003, J Biol Regul Homeost Agents.  17 (4): 330-333.
        • Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
        • Lebbink,R.J. et al., 2009,  Matrix Biol.  28 (4):202-210.

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