JunB Antibodies, cDNA Clones Research Reagents

JUNB (JunB Proto-Oncogene, AP-1 Transcription Factor Subunit) is a protein coding gene located on human chromosome 19p13.13. JUNB is also known as AP-1. The human JUNB gene encodes a 35879 Da protein containing 347 amino acids. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and G-protein signaling Ras family GTPases in kinase cascades (scheme). JUNB is related to DNA-binding transcription factor activity and transcription factor binding. JUN is an important paralog of JUNB gene. JUNB is associated with some diseases, including Primary Cutaneous T-Cell Lymphoma and Anaplastic Large Cell Lymphoma.

JunB Antibody (1)

    JunB cDNA Clone (2)

    NM_002229.2

    In expression vector

    In lentiviral vector

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    JunB Background

    JUNB, a subunit of the AP-1 transcription factor complex, mediates gene regulation in response to a plethora of extracellular stimuli. Previously, JUNB was shown to act as a critical positive regulator of blood vessel development and homeostasis as well as a negative regulator of proliferation, inflammation and tumor growth.

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