Integrin alpha V/ITGAV Antibodies, cDNA Clones Research Reagents

ITGAV (Integrin Subunit Alpha V, also known as CD51; MSK8; VNRA; VTNR), located on 2q32.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The gene produces a 116038 Da protein composed of 1048 amino acids. The product of this gene belongs to the integrin alpha chain family. The integrin alpha(v)beta3, whose alpha(v) subunit is encoded by the ITGAV gene, plays a key role in angiogenesis. Diseases such as West Nile Virus and Herpes Simplex are associated with ITGAV. The related pathways of ITGAV include Integrin Pathway and Signaling by GPCR.
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All Integrin alpha V/ITGAV Reagents

Integrin alpha V/ITGAV General Information

Integrin alpha V/ITGAV Antibody (3)

Application:
Clonality:
Host:

    Integrin alpha V/ITGAV cDNA Clone (27)

    NM_002210.4

    In cloning vector

    In cloning vector

    In expression vector

    untagged

    C-GFPSpark C-OFPSpark N-DDK tag C-His tag N-His tag C-HA tag N-HA tag C-Myc N-Myc

    In lentiviral vector

    C-GFPSpark
    NM_008402.2

    In cloning vector

    In cloning vector

    In expression vector

    untagged

    C-GFPSpark C-OFPSpark C-DDK tag N-DDK tag C-His tag N-His tag C-HA tag N-HA tag C-Myc N-Myc

    In lentiviral vector

    C-GFPSpark
    NM_001106549.1

    In cloning vector

    In cloning vector

    In lentiviral vector

    C-GFPSpark

    Integrin alpha V/ITGAV qPCR Primer (3)

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    Integrin alpha V/ITGAV Background

    ITGAV (Integrin Subunit Alpha V) is a Protein Coding gene. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. The subunit associates with beta 1, beta 3, beta 5, beta 6, and beta 8 subunits. The members of the integrin alpha V (ITGAV) family are widely expressed on many types of tumors and have been reported to be involved in angiogenesis, tumor metastases, and multicellular radioresistance. Recently, it has been shown that the polymorphism of the integrin-alpha V subunit encoded by the ITGAV gene plays a role in angiogenesis and is considered as RA susceptibility loci. The integrin alpha(v)beta3, whose alpha(v) subunit is encoded by the ITGAV gene, plays a key role in angiogenesis.

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