Glut4/SLC2A4 Antibodies, cDNA Clones Research Reagents

SLC2A4 (Solute Carrier Family 2 Member 4) is a protein coding gene located on human chromosome 17p13.1. SLC2A4 is also known as GLUT4. The human SLC2A4 gene encodes a 54787 Da protein containing 509 amino acids. The SLC2A4 protein is biasedly expressed in heart, fat and other tissues. Among its related pathways are HIF1Alpha Pathway and Beta-Adrenergic Signaling. SLC2A4 is related to transmembrane transporter activity and glucose transmembrane transporter activity. SLC2A1 is an important paralog of SLC2A4 gene. SLC2A4 is associated with some diseases, including Diabetes Mellitus, Noninsulin-Dependent and Diabetes Mellitus.
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All Glut4/SLC2A4 Reagents

Glut4/SLC2A4 General Information

Glut4/SLC2A4 Antibody (1)

Application:
Clonality:
Host:

    Glut4/SLC2A4 cDNA Clone (29)

    NM_001042.2

    In cloning vector

    In cloning vector

    In expression vector

    untagged

    C-GFPSpark C-OFPSpark C-DDK tag N-DDK tag C-His tag N-His tag C-HA tag N-HA tag C-Myc N-Myc

    In lentiviral vector

    C-GFPSpark
    NM_012751.1

    In expression vector

    untagged

    Glut4/SLC2A4 qPCR Primer (1)

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    Glut4/SLC2A4 Background

    GLUT4 content and its activation as well as SLC2A4 gene expression level are decreased in patients with type 2 diabetes. GLUT4 -coded by SLC2A4 (17p13) is an insulin-sensitive transporter with a critical role in glucose homeostasis and diabetes pathogenesis, preferentially expressed in the adipose tissue, heart muscle and skeletal muscle. We tested the hypothesis that natural selection acted on SLC2A4.

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