GABARAPL1 Proteins, cDNA Clones Research Reagents

All GABARAPL1 reagents are produced in house and quality controlled, including 19 GABARAPL1 Gene, 1 GABARAPL1 Protein, 1 GABARAPL1 qPCR. All GABARAPL1 reagents are ready to use.

GABARAPL1 Protein (1)

    GABARAPL1 cDNA Clone (19)


    In cloning vector

    In lentiviral vector


    In cloning vector

    In lentiviral vector

    GABARAPL1 qPCR Primer (1)

    GABARAPL1 Background

    ATG8, also known as GABARAPL1, is a ubiquitin-like protein which has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient depletion or rapamycin treatment and leads to the response of more than 3 autophagy-related (ATG) genes known so far, including ATG8.

    GABARAPL1 References

    • Ohsumi Y, et al. (2004) The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8. Genes Cells. 9(7):611-8.
    • Geng J, et al. (2008) The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep. 9(9):859-644.
    • Suzuki NN, et al. (2005) The crystal structure of plant ATG12 and its biological implication in autophagy. Autophagy. 1(2):119-126.

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