Cystatin SN Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Cystatin SN reagents are produced in house and quality controlled, including 7 Cystatin SN Antibody, 1 Cystatin SN ELISA, 13 Cystatin SN Gene, 1 Cystatin SN Lysate, 1 Cystatin SN Protein, 1 Cystatin SN qPCR. All Cystatin SN reagents are ready to use.

Cystatin SN Protein (1)

    Cystatin SN Antibody (7)

      Cystatin SN ELISA Kit & Match Antibody ELISA Pair Set (1)

      Cystatin SN cDNA Clone (13)

      NM_001898.2

      Cystatin SN qPCR Primer (1)

      Cystatin SN Lysate (1)

        Cystatin SN Background

        Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. Cystatin-SN / CST1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Cystatin-SN / CST1 is also expressed in saliva, tears, urine and seminal fluid. Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Human salivary cystatins include Cystatin-S, Cystatin-S1, Cystatin-S2, Cystatin- SA, Cystatin-SN, Cystatin-C and Cystatin-D. Cystatin-SN is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin-S, although both inhibit ficin equally well.

        Cystatin SN References

        • Saitoh E., et al.,(1987), Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family. Gene 61:329-338.
        • Al-Hashimi I., et al., (1988), Purification, molecular cloning, and sequencing of salivary cystatin SA-1.J. Biol. Chem. 263:9381-9387.
        • Deloukas P., et al.,(2001), The DNA sequence and comparative analysis of human chromosome 20.Nature 414:865-871.

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