Cystatin SA Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Cystatin SA reagents are produced in house and quality controlled, including 5 Cystatin SA Antibody, 1 Cystatin SA ELISA, 13 Cystatin SA Gene, 1 Cystatin SA Lysate, 1 Cystatin SA Protein, 1 Cystatin SA qPCR. All Cystatin SA reagents are ready to use.

Cystatin SA Protein (1)

    Cystatin SA Antibody (5)

      Cystatin SA ELISA Kit & Match Antibody ELISA Pair Set (1)

      Cystatin SA cDNA Clone (13)

      NM_001322.2

      Cystatin SA qPCR Primer (1)

      Cystatin SA Lysate (1)

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        Cystatin SA Background

        Cystatin-SA, also known as Cystatin-2, Cystatin-S5 and CST2, is a secreted protein which belongs to thecystatin family. Cystatin-2 / CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). It is also expressed in submandibular gland and parotid gland. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The CST1, CST2, CST4, and CST5 are expressed in differential, tissue-specific patterns. Expression of CST2 and CST5 is restricted to the submandibular and parotid glands, while CST1 and CST4 are expressed in these tissues and in the lacrimal gland.

        Cystatin SA References

        • Saitoh E., et al.,(1987), Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family. Gene 61:329-338.
        • Zhang Z., et al., (2004), Signal peptide prediction based on analysis of experimentally verified cleavage sites.Protein Sci. 13:2819-2824.
        • Deloukas P., et al.,(2001), The DNA sequence and comparative analysis of human chromosome 20.Nature 414:865-871.

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