CREB3L1 Proteins, Antibodies, cDNA Clones Research Reagents

All CREB3L1 reagents are produced in house and quality controlled, including 2 CREB3L1 Antibody, 1 CREB3L1 Gene, 1 CREB3L1 Lysate, 1 CREB3L1 Protein. All CREB3L1 reagents are ready to use.

CREB3L1 Protein (1)

    CREB3L1 Antibody (2)

      CREB3L1 cDNA Clone (1)


      In expression vector

      CREB3L1 Lysate (1)

        CREB3L1 Background

        CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.

        CREB3L1 References

        • Denard B. et al., 2011, Cell Host Microbe. 10 (1): 65-74.
        • Debelenko LV. et al., 2011, 50 (12): 1054-62.
        • Vellanki. et al., 2010, Endocrinology. 151 (9): 4146.

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