CNPY2 Proteins, Antibodies, cDNA Clones Research Reagents

All CNPY2 reagents are produced in house and quality controlled, including 1 CNPY2 Antibody, 26 CNPY2 Gene, 1 CNPY2 IP Kit, 1 CNPY2 Lysate, 1 CNPY2 Protein, 1 CNPY2 qPCR. All CNPY2 reagents are ready to use.

CNPY2 Protein (1)

    CNPY2 Antibody (1)

      CNPY2 cDNA Clone (26)

      BC065015
      NM_019953.1

      CNPY2 qPCR Primer (1)

      CNPY2 Lysate (1)

        CNPY2 Background

        CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. It is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. Downregulation of CNPY2 by RNA interference significantly decreased glioma cell migration and phosphorylation of MRLC. Inhibition of the corresponding MRLC kinase by ML-7 did not affect migration of CNPY2-overexpressing cells.

        CNPY2 References

        • Trynka G, et al. (2009) Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Gut. 58(8):1078-83.
        • Danielsen JM, et al. (2011) Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Mol Cell Proteomics. 10(3):M110.003590.
        • Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.

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