CHL1 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All CHL1 reagents are produced in house and quality controlled, including 6 CHL1 Antibody, 2 CHL1 ELISA, 12 CHL1 Gene, 4 CHL1 Lysate, 4 CHL1 Protein, 1 CHL1 qPCR. All CHL1 reagents are ready to use.

CHL1 Protein (4)

    CHL1 Antibody (6)

      CHL1 ELISA Kit & Match Antibody ELISA Pair Set (2)

      CHL1 cDNA Clone (12)

      CHL1 qPCR Primer (1)

      CHL1 Lysate (4)

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        CHL1 Background

        Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 3 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin typeⅢ domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease.

        CHL1 References

        • Alevizopoulos A, et al. (1997) Regulation of the Transforming Growth Factor beta-responsive Transcription Factor CTF-1 by Calcineurin and Calcium/ Calmodulin-dependent Protein Kinase IV. The Journal of Biological Chemistry. 272: 23597-605.
        • Gerring SL, et al. (1990) The CHL1 (CTF 1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2 / M. EMBO J. 9 (13): 4347-58.
        • Wei MH, et al. (1998) In silico-initiated cloning and molecular characterization of a novel human member of the L1 gene family of neural cell adhesion molecules. Human Genetics. 103 (3): 355-64.

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