CEACAM6 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All CEACAM6 reagents are produced in house and quality controlled, including 19 CEACAM6 Antibody, 3 CEACAM6 ELISA, 14 CEACAM6 Gene, 2 CEACAM6 Lysate, 3 CEACAM6 Protein, 1 CEACAM6 qPCR. All CEACAM6 reagents are ready to use.

CEACAM6 Protein (3)

    CEACAM6 Antibody (19)

      CEACAM6 ELISA Kit & Match Antibody ELISA Pair Set (3)

      CEACAM6 cDNA Clone (14)

      NM_002483.4
      XM_005589431.2

      In expression vector

      CEACAM6 qPCR Primer (1)

      CEACAM6 Lysate (2)

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        CEACAM6 Background

        Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.

        CEACAM6 References

        • Duxbury MS, et al. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 23(34): 5834-42.
        • Lewis-Wambi JS, et al. (2008) Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells. Eur J Cancer. 44(12): 1770-9.

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