Anti-Carbonic Anhydrase VIII/CA8 Antibody (Rabbit Polyclonal antibody) General Information
Anti-Carbonic Anhydrase VIII/CA8 Antibody
Reacts with: Mouse
Mouse Carbonic Anhydrase VIII/CA8
Recombinant Mouse Carbonic Anhydrase VIII / CA8 protein (Catalog#50767-M08E)
Produced in rabbits immunized with purified, recombinant Mouse Carbonic Anhydrase VIII / CA8 (Catalog#50767-M08E; P28651; Met1-Gln291). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Carbonic Anhydrase VIII/CA8 Background Information
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.
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