Anti-Carbonic Anhydrase VIII/CA8 Antibody


Anti-Carbonic Anhydrase VIII/CA8 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Carbonic Anhydrase VIII/CA8 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse Carbonic Anhydrase VIII/CA8
Recombinant Mouse Carbonic Anhydrase VIII / CA8 protein (Catalog#50767-M08E)
Produced in rabbits immunized with purified, recombinant Mouse Carbonic Anhydrase VIII / CA8 (Catalog#50767-M08E; P28651; Met1-Gln291). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Carbonic Anhydrase VIII/CA8 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Carbonic Anhydrase VIII/CA8 Antibody: Alternative Names

Anti-AW546993 Antibody; Anti-Ca8 Antibody; Anti-Cals Antibody; Anti-Cals1 Antibody; Anti-Car8 Antibody; Anti-Carp Antibody; Anti-RP23-180H12.1 Antibody; Anti-wdl Antibody

Carbonic Anhydrase VIII/CA8 Background Information

The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.
Full Name
carbonic anhydrase VIII
  • Lehtonen J, et al. (2004) Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family. The Journal of Biological Chemistry. 279: 2719-27.
  • Lindskog S. (1997) Structure and mechanism of carbonic anhydrase. Pharmacology & Therapeutics. 74(1):1-20.
  • Miyaji E, et al. (2003) Overexpression of carbonic anhydrase-related protein VIII in human colorectal cancer. The Journal of Pathology. 201(1): 37-45.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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