Recombinant Anti-CD48 Antibody (PerCP), Rabbit Monoclonal

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Recombinant Anti-CD48 Antibody (PerCP), Rabbit Monoclonal General Information

Product name
Recombinant Anti-CD48 Antibody (PerCP), Rabbit Monoclonal
Validated applications
FCM
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD48
Immunogen
Recombinant Mouse CD48 protein (Catalog#50415-M08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48 / SLAMF2 (rM CD48 / SLAMF2; Catalog#50415-M08H; NP_031675.1; Met 1-Arg 216) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed.
Source
Monoclonal Rabbit IgG Clone #341
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
PerCP
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Recombinant Anti-CD48 Antibody (PerCP), Rabbit Monoclonal Images

Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 (Cat. No. 553141) and stained with PerCP-conjugated anti-Mouse CD48 (50415-R341-C). The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.

Recombinant Anti-CD48 Antibody (PerCP), Rabbit Monoclonal: Synonyms

Anti-AI449234 Antibody; Anti-AW610730 Antibody; Anti-Bcm-1 Antibody; Anti-BCM1 Antibody; Anti-BLAST Antibody; Anti-BLAST-1 Antibody; Anti-BLAST1 Antibody; Anti-MEM-102 Antibody; Anti-Sgp-60 Antibody; Anti-SLAMF2 Antibody

CD48 Background Information

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
Full Name
CD48 molecule
Research Areas
References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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