Anti-XCL2 Antibody, Mouse Monoclonal General Information
Anti-XCL2 Antibody, Mouse Monoclonal
Reacts with: Human
Recombinant Human XCL2 Protein (Catalog#13502-H08B)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human XCL2 (rh XCL2; Catalog#13502-H08B; Q9UBD3; Met1-Gly114). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #06
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
XCL2 is a small cytokine belonging to the XC chemokine family. Chemokines are a group of cytokines. Members of this group of so-called C-Chemokines belong to the SCY family of cytokines and are designated XCL (L for ligand) followed by a number. XCL2 is the new designation of SCM-1-beta. XCL2 is highly related to another chemokine called XCL1. XCL2 gene is located on chromosome 1 in humans. XCL2 is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1. XCL2 gene has been proposed to participate in pathways (Chemokine signaling pathway, Cytokine-cytokine receptor interaction) and processes (blood circulation, signal transduction, chemotaxis, immune response). XCL2 are expected to have molecular function (chemokine activity) and to localize in various compartments (extracellular space, extracellular region). A putative protein interactor has been described (XCR1). The spliced mRNA putatively encodes a good protein, containing small cytokines (intecrine / chemokine), interleukin-8 like domain; the complete protein appears to be secreted.
chemokine (C motif) ligand 2
Kennedy J, et al. (1995) Molecular cloning and functional characterization of human lymphotactin. J Immunol. 155(1):203-9.
Yoshida T, et al. (1998) Identification of single C motif-1 / lymphotactin receptor XCR. J Biol Chem. 273(26):16551-54.
Yoshida T, et al. (1996) Structure and expression of two highly related genes encoding SCM-1 / human lymphotactin. FEBS Lett. 395(1):82-8.
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