Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal

RRID Number: AB_2860384
EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal General Information

Product name
Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human LYPD3
Immunogen
Recombinant Human C4.4A / LYPD3 protein (Catalog#11836-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human C4.4A / LYPD3 (rh C4.4A / LYPD3; Catalog#11836-H08H; NP_055215.2; Met1-His286) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Source
Monoclonal Rabbit IgG Clone #213
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.03%ProClin300
Conjugate
APC
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze !

Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal Images

Flow cytometric analysis of Human LYPD3 expression on PC-3 cells.

Citation List

Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal: Synonyms

Anti-C4.4A Antibody

LYPD3 Background Information

Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4 and LYPD3, is a cell membrane protein which contains twoUPAR/Ly6 domains. Human LYPD3 contains twoUPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression
Full Name
LY6/PLAUR domain containing 3
References
  • Smith B.A., et al., 2001, Cancer Res. 61:1678-85.
  • Wuerfel J., et al., 2001, Gene 262:35-41.
  • Clark H.F., et al., 2003, Genome Res. 13:2265-70.
  • Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-85.
  • Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-57.

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