Anti-Interferon Gamma Antibody (PerCP) (Rabbit Monoclonal antibody) General Information
Anti-Interferon Gamma Antibody (PerCP)
Reacts with: Human
Human Interferon Gamma
Recombinant Human Interferon Gamma/IFN gamma/IFNG Protein (Catalog#11725-HNAS)
This antibody was obtained from a rabbit immunized with purified, recombinant Human Interferon Gamma/IFN gamma/IFNG (rh Interferon Gamma/IFN gamma/IFNG; Catalog#11725-HNAS; NP_000610.2; Met1-Gln166) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed.
Monoclonal Rabbit IgG Clone #003
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
5 μl/Test, 0.1 mg/ml
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.
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