Recombinant Anti-CD48 Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-CD48 Antibody, Rabbit Monoclonal General Information

Product name
Recombinant Anti-CD48 Antibody, Rabbit Monoclonal
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Human
Specificity
Human CD48
No cross-reactivity in ELISA with
Mouse CD48
Human TNFRSF4
Immunogen
Recombinant Human CD48 / SLAMF2 Protein (Catalog#10797-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD48 / SLAMF2 (rh CD48 / SLAMF2; Catalog#10797-H08H; NP_001769.2; Met 1-Ser 220).
Source
Monoclonal Rabbit IgG Clone #007
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-CD48 Antibody, Rabbit Monoclonal Validated Applications

Application Dilution
ELISA 1:5000-1:10000
ELISA(Det) 1:1000-1:10000
Notes
ELISA(Det): This antibody will detect Human CD48 / Blast-1 in ELISA pair set (Catalog: # SEKA10797). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10797-MM02).
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-CD48 Antibody, Rabbit Monoclonal: Synonyms

Anti-BCM1 Antibody; Anti-BLAST Antibody; Anti-Blast-1 Antibody; Anti-BLAST1 Antibody; Anti-hCD48 Antibody; Anti-mCD48 Antibody; Anti-MEM-102 Antibody; Anti-SLAMF2 Antibody

CD48 Background Information

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
Full Name
CD48 molecule
Research Areas
References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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