Anti-CD48 Antibody, Mouse Monoclonal

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Anti-CD48 Antibody, Mouse Monoclonal General Information

Product name
Anti-CD48 Antibody, Mouse Monoclonal
Validated applications
ELISA(Cap)
Species reactivity
Reacts with: Human
Specificity
Human CD48
Immunogen
Recombinant Human CD48 protein (Catalog#10797-H08H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD48 (rhCD48; Catalog#10797-H08H; NP_001769.2; Met 1-Ser 220). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #9B1A3F6
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CD48 Antibody, Mouse Monoclonal Validated Applications

Notes
ELISA(Cap): This antibody will detect Human CD48 / Blast-1 in ELISA pair set (Catalog: # SEKA10797). In a sandwich ELISA, it can be used as capture antibody when paired with (Catalog: # 10797-R007).
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CD48 Antibody, Mouse Monoclonal: Synonyms

Anti-BCM1 Antibody; Anti-BLAST Antibody; Anti-Blast-1 Antibody; Anti-BLAST1 Antibody; Anti-hCD48 Antibody; Anti-mCD48 Antibody; Anti-MEM-102 Antibody; Anti-SLAMF2 Antibody

CD48 Background Information

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
Full Name
CD48 molecule
Research Areas
References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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