Anti-CD28 Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Anti-CD28 Antibody (FITC)
Reacts with: Human
Recombinant Human CD28 Protein (Catalog#11524-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD28 (rh CD28; Catalog#11524-H08H; P10747-1; Met1-Pro152) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Monoclonal Rabbit IgG Clone #007
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
5 μl/Test, 0.1 mg/ml
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Flow cytometric analysis of Human CD28 expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human CD28. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Anti-CD28 Antibody (FITC): Alternative Names
CD28 Background Information
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
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