Anti-Fractalkine Antibody


Anti-Fractalkine Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Fractalkine Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Fractalkine
E. coli-derived Human Fractalkine / CX3CL1 fragment
Produced in rabbits immunized with E. coli-derived Human Fractalkine / CX3CL1 fragment, and purified by antigen affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
PBS, pH7.0 with 0.03% Proclin300
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Anti-Fractalkine Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
IHC-P 1:200-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Fractalkine Antibody (Rabbit Polyclonal antibody) Images

Immunochemical staining of human CX3CL1 in human kidney with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.
Immunochemical staining of human CX3CL1 in human skeletal muscle with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.

Anti-Fractalkine Antibody: Alternative Names

Anti-ABCD-3 Antibody; Anti-C3Xkine Antibody; Anti-CXC3 Antibody; Anti-CXC3C Antibody; Anti-fractalkine Antibody; Anti-neurotactin Antibody; Anti-NTN Antibody; Anti-NTT Antibody; Anti-SCYD1 Antibody

Fractalkine Background Information

Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines.
Full Name
chemokine (C-X3-C motif) ligand 1
  • Imai T, et al. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell. 91(4): 521-30.
  • Papadopoulos EJ, et al. (1999) Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. Eur J Immunol. 29 (8): 2551-9.
  • Umehara H, et al. (2004) Fractalkine in vascular biology: from basic research to clinical disease". Arterioscler. Thromb Vasc Biol. 24 (1): 34-40.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait