ANK/ANKH cDNA Clone: Expression and Clone Vector / Plasmid

ANK/ANKH cDNA / Gene Overview

ANKH cDNA / gene is a gene with protein product which located on 5p15.2. The ANKH gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 238 organisms have orthologs with human gene ANKH.

ANK/ANKH cDNA / Gene Function

This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]

ANK/ANKH cDNA / Gene Sequence

LOCUS
AF274753 1568 bp mRNA linear PRI 27-JUL-2000
DEFINITION
Homo sapiens progressive ankylosis-like protein (ANK) mRNA, complete cds.
ACCESSION
AF274753
VERSION
AF274753.1

This sequence information is just for reference only.

ANK/ANKH Family & Reagents

Gene family

ANK/ANKH Gene family reagents (Solute carriers)

Approved Symbol Reagent list
NPC1
SLC3A2
Approved Symbol Reagent list
SLC27A4
   

ANK/ANKH cDNA / Gene Alias

  • ANK
  • CPPDD
  • HANK
  • SLC62A1

ANK/ANKH cDNA / Gene Expression

Ubiquitous expression in prostate (RPKM 21.9), brain (RPKM 17.0) and 25 other tissues