ANK/ANKH cDNA Clone: Expression and Clone Vector / Plasmid
ANK/ANKH cDNA / Gene Overview
ANKH cDNA / gene is a gene with protein product which located on 5p15.2. The ANKH gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 238 organisms have orthologs with human gene ANKH.
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]
ANK/ANKH cDNA / Gene Sequence
AF274753 1568 bp mRNA linear PRI 27-JUL-2000
Homo sapiens progressive ankylosis-like protein (ANK) mRNA, complete cds.
This sequence information is just for reference only.
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