CXCR5 (Protein | Antibody | cDNA Clone | ELISA Kit)

All CXCR5 reagents are produced in house and quality controlled, including 1 CXCR5 Antibody, 27 CXCR5 Gene, 1 CXCR5 qPCR. All CXCR5 reagents are ready to use.

CXCR5 Background

Because of the level of attention it received due to its role as the principal HIV coreceptor, CCR5 has been described as a 'celebrity' chemokine receptor. The wealth of CCR5-related tools that have been developed during the intensive investigation of CCR5 as an HIV drug target can now be turned towards the study of CCR5 as a model chemokine receptor. The enforced expression of CXCR5 onto Treg cells efficiently induces Tfr cell-like properties, which might be a promising cellular therapeutic approach for the treatment of antibody-mediated autoimmune diseases. The Chemokine receptor 5 (CCR5) is implicated in immune cell migration and cytokine release in the CNS, and it was demonstrated to strongly contribute to CNS inflammation and damage in several models of sterile and pathogen-mediated CNS diseases.