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CD14 抗體, 鼠單抗

  • CD14 Antibody, Mouse MAb, Flow cytometric analysis
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 CD14 抗體產品資訊
免疫原:Recombinant Human CD14 protein (Catalog#10073-H08H)
Clone ID:06
Ig類型:Mouse IgG1
濃度:
內毒素:
緩衝液:0.2 μm filtered solution in PBS with 5% trehalose
抗體製備方法:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD14 (rh CD14; Catalog#10073-H08H; NP_000582.1; Met1-Met344). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
 CD14 Antibody FC Application Image
CD14 Antibody, Mouse MAb, Flow cytometric analysis
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Caption:
Flow cytometric analysis of Human CD14 expression on human peripheral blood monocytes. Cells were stained with purified Mouse anti-Human CD14, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of viable monocytes.
Other CD14 Antibody Products
CD14 研究背景

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

 CD14 參考資料
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • SD Wright, et al. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249 (4975): 1431-3.
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    貨號: 10073-MM06-200
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    Datasheet & Documentation

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