TIGIT Protein

TIGIT Protein Sequence

Species Human TIGIT protein
Length 244
Mass (Da) 26319
Sequence Human TIGIT protein sequence
Species Mouse TIGIT protein
Length 249
Mass (Da) 26959
Sequence Mouse TIGIT protein sequence
Species
Length
Mass (Da)
Sequence

TIGIT Protein Molecular Weight & PI

T-cell immunoreceptor with Ig and ITIM domains precursor (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 22-244 T-cell immunoreceptor with Ig and ITIM

Molecular weight (Da)

23953.1

Theoretical pI

5.19

TIGIT Protein Structure

Crystal structure of the immunoreceptor TIGIT IgV domain
Deposited
2011-10-27   Released:  2012-03-14
Deposition Author(s)
Yin, J.P., Stengel, K.F., Rouge, L., Bazan, J.F., Wiesmann, C.
Organism(s)
Homo sapiens
Expression System
Escherichia coli
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.6270 Å
R-Value Free
0.274
R-Value Work
0.215
3UCR From PDB

Human TIGIT protein Secondary structure

TIGIT Protein Interaction

Recombinant TIGIT Protein Feature

TIGIT Protein, Human, Recombinant (His Tag)

High Purity
> 90 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
High Activity
1. Measured by its ability to bind with human CD155-Fc (Cat:10109-H02H) in a functional ELISA. 2. Measured by its ability to bind with mouse PVR-Fch (Cat:50259-M03H) in a functional ELISA.

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