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RYK  Protein, Antibody, ELISA Kit, cDNA Clone

RYK 相关研究领域

RYK 相關信號通路

    RYK 概述&蛋白信息

    RYK 研究背景

    催化活性: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. {ECO:0000255|PROSITE-ProRule:PRU10028}.
    亞單位結構: Interacts with DVL1 (via PDZ domain). {ECO:0000269|PubMed:15454084}.
    結構域: The extracellular WIF domain is responsible for Wnt binding. {ECO:0000250}.
    亞細胞定位: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus. {ECO:0000250}.
    組織特異性: Observed in all the tissues examined.
    翻譯後修飾: Proteolytically cleaved, in part by presenilin, in response to WNT3 stimulation. Cleavage occurs during neuronal differentiation. {ECO:0000269|PubMed:16116452}.
    相似的序列: Belongs to the protein kinase superfamily. Tyr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.; Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.; Contains 1 WIF domain. {ECO:0000255|PROSITE-ProRule:PRU00222}.
    General information above from UniProt

    RYK 別稱

    RYK 相關文獻

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