Anti-PIGR Antibody


Anti-PIGR Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-PIGR Antibody
Validated applications
Species reactivity
Reacts with: Human
Human PIGR
Recombinant Human PIGR protein (Catalog#10131-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human PIGR (rh PIGR; Catalog#10131-H08H; NP_002635.2; Met1-Arg638,365Ser/Gly).
Monoclonal Rabbit IgG Clone #007
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-PIGR Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
IHC-P 1:50-1:200
ICC-IF 1:20-1:100
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-PIGR Antibody (Rabbit Monoclonal antibody) Images

Immunochemical staining of human PIGR in human liver (cirrhosis) with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte.
Immunochemical staining of human PIGR in human breast carcinoma with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
Immunofluorescence staining of PIGR in HepG2 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Y PIGR monoclonal antibody (dilution ratio 1:60) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.

Anti-PIGR Antibody: Alternative Names

Anti-FLJ22667 Antibody; Anti-MGC125361 Antibody; Anti-MGC125362 Antibody; Anti-PIGR Antibody

PIGR Background Information

Polymeric immunoglobulin receptor, also known asPIGR, is a member of the immunoglobulin superfamilyand aFc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion ofIgAandIgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
Full Name
polymeric immunoglobulin receptor
  • Coyne, R. S. et al., 1995, J. Biol. Chem. 269 (50) :31620-31625. 
  • Kaetzel,C.S., 2001,  Curr Biol. 11(1): R35-38.
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