MMP12 cDNA Clone: Expression and Clone Vector / Plasmid
MMP12 cDNA / Gene Overview
MMP12 gene / cDNA is a protein-coding gene which located on 11q22.2. The MMP12 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.102 organisms have orthologs with human gene MMP12.
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
MMP12 cDNA / Gene Sequence
LOCUS NM_002426 1881 bp mRNA linear PRI 12-AUG-2018
Homo sapiens matrix metallopeptidase 12 (MMP12), mRNA.
This sequence information is just for reference only.
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