MBL2 gene / cDNA is a protein-coding gene which located on 10q21.1. The MBL2 gene is conserved in chimpanzee, Rhesus monkey, cow, mouse, rat, chicken, zebrafish, and frog.100 organisms have orthologs with human gene MBL2.
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]
Mannan Binding Lectin / MBL2 cDNA / Gene Sequence
LOCUS NM_000242 3569 bp mRNA linear PRI 12-AUG-2018
Homo sapiens mannose binding lectin 2 (MBL2), mRNA.
This sequence information is just for reference only.
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