LIGHT cDNA Clone: Expression and Clone Vector / Plasmid
LIGHT cDNA / Gene Overview
TNFSF14 gene / cDNA is a protein-coding gene which located on 19p13.3. The TNFSF14 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.133 organisms have orthologs with human gene TNFSF14.
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
LIGHT cDNA / Gene Sequence
LOCUS NM_003807 4807 bp mRNA linear PRI 01-JUL-2018
Homo sapiens TNF superfamily member 14 (TNFSF14), transcript variant 1, mRNA.
This sequence information is just for reference only.
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