Anti-Insulin Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human Insulin / INS Protein (Catalog#11038-HNAY)
Produced in rabbits immunized with purified, recombinant Human Insulin / INS (rh Insulin / INS; Catalog#11038-HNAY; INS_HUMAN; Phe1-Lys29 & Gly1-Asn21). Insulin / INS specific IgG was purified by Human Insulin / INS affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Veedfald S, Plamboeck A, Deacon C F, et al. Cephalic phase secretion of insulin and other enteropancreatic hormones in humans[J]. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016, 310(1): G43-G51.
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