HVEM cDNA Clone: Expression and Clone Vector / Plasmid

HVEM cDNA / Gene Overview

TNFRSF14 gene / cDNA is a protein-coding gene which located on 1p36.32. The TNFRSF14 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, zebrafish, and frog.108 organisms have orthologs with human gene TNFRSF14.

HVEM cDNA / Gene Function

This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

HVEM cDNA / Gene Sequence

LOCUS
LOCUS NM_001297605 3376 bp mRNA linear PRI 05-AUG-2018
DEFINITION
Homo sapiens TNF receptor superfamily member 14 (TNFRSF14), transcript variant 2, mRNA.
ACCESSION
NM_001297605
VERSION
NM_001297605.1

This sequence information is just for reference only.

HVEM Family & Reagents

HVEM Gene family reagents (CD molecules)

Approved Symbol Reagent list
B3gat1
CD8A
IL18R1
PTPRJ
SLAMF6
LILRB5
CDCP1
MELTF
MUC1
IL9R
Approved Symbol Reagent list
ART1
LILRB1
CD99
SELE
BSG
FGFR1
PECAM1
GP1BA
NCAM1
CD44

HVEM Gene family reagents (Tumor necrosis factor receptor superfamily)

Approved Symbol Reagent list
NGFR
TNFRSF10C
TNFRSF19
TNFRSF6B
TNFRSF10D
TNFRSF1B
EDAR
RELT
LTBR
CD40
Approved Symbol Reagent list
FAS
CD27
TNFRSF25
TNFRSF9
TNFRSF10A
TNFRSF13B
TNFRSF1A
EDA2R
TNFRSF17
TNFRSF11A

HVEM cDNA / Gene Alias

  • ATAR
  • CD270
  • herpesvirus entry mediator
  • HVEA
  • HVEM
  • LIGHTR
  • TR2

HVEM cDNA / Gene Expression

Ubiquitous expression in spleen (RPKM 22.9), duodenum (RPKM 21.7) and 23 other tissues