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 IL3/IL-3/Interleukin-3  蛋白

All IL3 Reagents

描述: Active  
表達宿主: Baculovirus-Insect Cells  
11858-H08B-5
11858-H08B-20
11858-H08B-100
5 µg 
20 µg 
100 µg 
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表達宿主: E. coli  
11858-HNAE-500
11858-HNAE-5
11858-HNAE-20
11858-HNAE-100
11858-HNAE-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
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表達宿主: Human Cells  
11858-H08H-50
11858-H08H-5
11858-H08H-100
11858-H08H-10
50 µg 
5 µg 
100 µg 
10 µg 
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IL3/IL-3/Interleukin-3 相关研究领域

IL3/IL-3/Interleukin-3 相關信號通路

    IL3/IL-3/Interleukin-3 相關蛋白、抗體、cDNA基因、ELISA試劑盒

    IL3/IL-3/Interleukin-3 概述&蛋白信息

    IL3/IL-3/Interleukin-3 研究背景

    基因概述: The protein encoded by IL-3 gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
    General information above from NCBI
    亞單位結構: Monomer.
    亞細胞定位: Secreted.
    組織特異性: Activated T-cells, mast cells, natural killer cells.
    相似的序列: Belongs to the IL-3 family. {ECO:0000305}.
    General information above from UniProt

    IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

    IL3/IL-3/Interleukin-3 別稱

    Interleukin-3, []
    IL-3,MCGF,MULTI-CSF, [homo-sapiens]
    IL3,IL-3,MCGF,MGC79398,MGC79399,MULTI-CSF, [human]
    Csfmu,MCGF,PSF,RP23-309E16.5,BPA,HCGF,Il3,IL-3, [mouse]
    BPA,PSF,HCGF,Il-3,MCGF,Csfmu, [mus-musculus]

    IL3/IL-3/Interleukin-3 相關文獻

  • Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
  • Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
  • Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.
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