快速訂購

FZD3/frizzled 3  Protein, Antibody, ELISA Kit, cDNA Clone

FZD3/frizzled 3 相关研究领域

FZD3/frizzled 3 相關信號通路

FZD3/frizzled 3 相關蛋白、抗體、cDNA基因、ELISA試劑盒

FZD3/frizzled 3 概述&蛋白信息

FZD3/frizzled 3 研究背景

亞單位結構: Interacts with VANGL2. {ECO:0000250}.
結構域: Lys-Thr-X-X-X-Trp motif interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway. {ECO:0000250}.; The FZ domain is involved in binding with Wnt ligands. {ECO:0000250}.
亞細胞定位: Membrane; Multi-pass membrane protein. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell surface {ECO:0000250|UniProtKB:Q61086}. Apical cell membrane {ECO:0000250|UniProtKB:Q61086}; Multi-pass membrane protein. Note=Colocalizes with FZD6 at the apical face of the cell (By similarity). {ECO:0000250|UniProtKB:Q61086}.
組織特異性: Widely expressed. Relatively high expression in the CNS, including regions of the limbic system, in kidney, pancreas, skeletal muscle, uterus and testis.
翻譯後修飾: Ubiquitinated by ZNRF3, leading to its degradation by the proteasome. {ECO:0000250}.
相似的序列: Belongs to the G-protein coupled receptor Fz/Smo family. {ECO:0000305}.; Contains 1 FZ (frizzled) domain. {ECO:0000255|PROSITE-ProRule:PRU00090}.
General information above from UniProt

FZD3/frizzled 3 別稱

Fz-3, [homo-sapiens]
Fz3,AU020229,D930050A07Rik, [mus-musculus]

FZD3/frizzled 3 相關文獻

請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”