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Cytokine Receptors

Cytokine receptors are cell surface receptors that bind specifically to cytokines and transduce their signals, including chemokine receptor, interleukin receptor, interferon receptor, tumor necrosis factor receptor (TNF receptor), colony-stimulating factor receptor (CSF receptor), growth factor receptors and TGF-beta superfamily receptors .
The patterns of expression of cytokine receptors are a product of differentiation and provide for changes in physiological regulation. These cytokine receptors enable cells to communicate with the extracellular environment by responding to signals generated in the vicinity or in other parts of the organism. Thus, the initial binding of cytokines to their receptors is a key event that occurs rapidly, at very low cytokine concentrations, is usually virtually irreversible, and leads to intracellular changes resulting in a biologic response. The biologic response can vary between cytokine receptors and from cell to cell but in general it involves gene expression, changes in the cell cycle, and release of mediators such as cytokines themselves.

Hot Cytokine Receptors Molecules List

<* Being developed. Tell us your requirement so that the products of interest be placed on the priority list.

ACVR2A ACVR2B/Activin RIIB MCSF Receptor/CSF1R/CD115
HER2/ERBB2 ERBB3/HER3 EPHA3/Eph Receptor A3
EGFR/HER1 IL3RA/CD123 IL6R/IL-6R/CD126
IL1RL1/IL-1 R4 IGF1R/CD221/IGF-I R LILRB4/CD85k/ILT3
IL17RA/IL-17RA/CD217 Insulin Receptor/INSR/CD220 IL2RA/IL-2RA/CD25
IL-4R/CD124 LILRB2/ILT4/LIR-2 CD122 / IL-2RB
IL7R/IL-7R/CD127 VEGFR2/KDR/Flk-1/CD309 LDLR/LDL R/LDL Receptor
PDGFRB/CD140b TNFR1/TNFRSF1A/CD120a TNFR2/TNFRSF1B/CD120b
4-1BB/TNFRSF9/CD137 TRAIL R1/CD261/TNFRSF10A TRAIL R2/CD262/TNFRSF10B
TRAIL R4/CD264/TNFRSF10D TRAILR3/TNFRSF10C TNFRSF11A
TACI/TNFRSF13B(CD267) HVEM/TNFRSF14/CD270 BCMA/TNFRSF17/CD269
GITR/TNFRSF18/CD357
請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”