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4-1BBL / CD137L 抗體, 兔多抗

產品資料評論實驗方法
表達宿主: Human Cells  
  • Slide 1
15693-H01H-5
15693-H01H-20
15693-H01H-100
5 µg 
20 µg 
100 µg 
Add to Cart
描述: Active  
表達宿主: Human Cells  
  • Slide 1
50067-M07H-50
50067-M07H-5
50067-M07H-20
50 µg 
5 µg 
20 µg 
Add to Cart
表達宿主: Human Cells  
  • Slide 1
80166-R01H-50
80166-R01H-20
50 µg 
20 µg 
Add to Cart
表達宿主: Human Cells  
  • Slide 1
80166-R07H-50
80166-R07H-20
50 µg 
20 µg 
Add to Cart

CD137L/4-1BBL/TNFSF9 AntibodyRelated Products

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CD137L/4-1BBL/TNFSF9 antibody 研究背景

4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In additon, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: FCM Antibodies
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

大鼠 CD137L/4-1BBL/TNFSF9 antibody 參考資料
  • Cheung CT, (2007) Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Lab Invest. 87(7): 651-61.
  • Wang C, et al. (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev. 229(1): 192-215.
  • Habib-Agahi M, et al. (2009) 4-1BBL costimulation retrieves CD28 expression in activated T cells. Cell Immunol. 256(1-2): 39-46.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”