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人 CNDP2 / CPGL / PEPA 蛋白 (His 標籤)

產品資料評論實驗方法
反應性: Mouse  
應用 : ELISA  WB  
    50246-R001-50
    50246-R001-100
    50 µg 
    100 µg 
    Add to Cart
    反應性: Mouse  
    應用 : ELISA  WB  IP  
    • Slide 1
    • Slide 1
    50246-RP02-50
    50246-RP02-100
    50 µg 
    100 µg 
    Add to Cart
    反應性: Mouse  
    應用 : IHC-P  
    • Slide 1
    50246-R210-50
    50246-R210-100
    50 µg 
    100 µg 
    Add to Cart
    反應性: Mouse  
    應用 : ELISA  
      50246-RP01-200
      50246-RP01-100
      200 µg 
      100 µg 
      Add to Cart

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      CNDP2 protein 研究背景

      Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.

       CNDP2 protein 參考資料
    • Bakker,SJ. et al., 2008, Diabetes  57 (12):e16; author reply e17. 
    • Wanic, K. et al., 2008, Diabetes  57 (9): 2547-51.
    • McDonough,CW. et al., 2009, Hum Genet 126 (2): 265-75.
    • Kaur,H. et al., 2009, J Biol Chem. 284 (21):14493-502.
    • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”