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小鼠 S100A9/MRP-14 基因全長cDNA ORF克隆 (表達載體), C-His 標籤

產品資料評論實驗方法
描述: Active  
表達宿主: E. coli  
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11145-HNAE-50
11145-HNAE-100
50 µg 
100 µg 
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描述: Active  
表達宿主: Baculovirus-Insect Cells  
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11145-H08B-50
11145-H08B-100
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100 µg 
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表達宿主: E. coli  
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50284-M07E-50
50284-M07E-100
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100 µg 
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反應性: Human  
應用 : ELISA  
    11145-RP01-400
    11145-RP01-200
    11145-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    反應性: Human  
    應用 : FCM  
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    11145-MM01-F-25
    11145-MM01-F-100
    25 Test 
    100 Tests 
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    反應性: Human  
    應用 : ELISA  IHC-P  
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    • Slide 1
    11145-RP02-50
    11145-RP02-200
    11145-RP02-100
    50 µg 
    200 µg 
    100 µg 
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    反應性: Human  
    應用 : IHC-P  
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    11145-R209-50
    11145-R209-100
    50 µg 
    100 µg 
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    反應性: Human  
    應用 : ELISA  WB  
      11145-R018-50
      11145-R018-100
      50 µg 
      100 µg 
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      反應性: Human  
      應用 : FCM  IF  ICC/IF  
      • Slide 1
      • Slide 1
      11145-MM01-50
      11145-MM01-200
      11145-MM01-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反應性: Human  
      應用 : FCM  
      • Slide 1
      11145-MM01-P-25
      11145-MM01-P-100
      25 Test 
      100 Tests 
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      反應性: Mouse  
      應用 : 
      • Slide 1
      50284-T24-50
      50284-T24-200
      50284-T24-100
      50 µg 
      200 µg 
      100 µg 
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      S100A9/MRP-14 cdna-clone 研究背景

      S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calcium-binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

      小鼠 S100A9/MRP-14 cdna-clone 參考資料
    • Miyasaki KT. et al., 1993, J Dent Res. 72: 517-23.
    • Fanò G. et al., 1995, Prog Neurobiol. 46 (1): 71-82.
    • Vogl T. et al., 2004, Blood. 104: 4260-8.
    • Viemann D. et al., 2005, Blood. 105: 2955-62.
    • Nakatani Y. et al., 2005, Mediators Inflamm. 2005: 280-92.
    • Bjoerk P. et al., 2009, PLoS Biol. 7: E97-E97.
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