Text Size:AAA

人 SCN2B 基因全長cDNA ORF克隆 (表達載體), N-HA 標籤

產品資料評論實驗方法
表達宿主: Human Cells  
  • Slide 1
13859-H08H-20
13859-H08H-100
20 µg 
100 µg 
Add to Cart
表達宿主: Human Cells  
  • Slide 1
13859-H02H-20
13859-H02H-100
20 µg 
100 µg 
Add to Cart
反應性: Human  
應用 : ELISA  
    13859-RP01-400
    13859-RP01-200
    13859-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
    反應性: Human  
    應用 : 
    • Slide 1
    13859-T24-50
    13859-T24-200
    13859-T24-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反應性: Human  
    應用 : ELISA  
      13859-T16-50
      13859-T16-200
      13859-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

      SCN2B cDNA ORF CloneRelated Products

      Related Products

      Featured Reagent Products

      SCN2B cdna-clone 研究背景

      SCN2B plays a key role in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which may be associated with either one or more beta-subunits. Alpha-subunits are composed for four homologous domains, each of which contains six transmembrane segments.They are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. SCN2B causes an increase in the plasma membrane surface area and in its folding into microvilli. SCN2B also interacts with TNR and may play a crucial role in clustering and regulation of activity of sodium channels at nodes of ranvier.

       SCN2B cdna-clone 參考資料
    • Kimura K, et al. (2006) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res. 16(1):55-65.
    • Tan BH, et al. (2010) Sudden infant death syndrome-associated mutations in the sodium channel beta subunits. Heart Rhythm. 7(6):771-8.
    • Watanabe H, et al. (2009) Mutations in sodium channel beta1- and beta2-subunits associated with atrial fibrillation. Circ Arrhythm Electrophysiol. 2(3):268-75. Kimura K et al., 2006, Genome Res. 16(1):55-65.
    • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”