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人 JAML / AMICA 蛋白 (His 標籤)

產品資料評論實驗方法
反應性: Human  
應用 : ELISA  
    10120-MM08-50
    10120-MM08-200
    10120-MM08-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反應性: Human  
    應用 : FCM  
    • Slide 1
    10120-MM02-50
    10120-MM02-200
    10120-MM02-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反應性: Human  
    應用 : 
      10120-MM06-50
      10120-MM06-200
      10120-MM06-100
      10120-MM06-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
      Add to Cart
      反應性: Human  
      應用 : ELISA  
        10120-RP02-50
        10120-RP02-200
        10120-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反應性: Human  
        應用 : FCM  
        • Slide 1
        • Slide 1
        10120-MM02-F-25
        10120-MM02-F-100
        25 Test 
        100 Tests 
        Add to Cart
        反應性: Human  
        應用 : FCM  
        • Slide 1
        10120-MM02-A-25
        10120-MM02-A-100
        25 Test 
        100 Tests 
        Add to Cart
        反應性: Human  
        應用 : 
          10120-MM05-50
          10120-MM05-200
          10120-MM05-100
          10120-MM05-1
          50 µg 
          200 µg 
          100 µg 
          1 mg 
          Add to Cart
          反應性: Human  
          應用 : ELISA  
            10120-RP01-400
            10120-RP01-200
            10120-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反應性: Human  
            應用 : FCM  
            • Slide 1
            • Slide 1
            10120-MM02-P-25
            10120-MM02-P-100
            25 Test 
            100 Tests 
            Add to Cart

            JAML/AMICA1 Recombinant ProteinRelated Products

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            JAML/AMICA1 protein 研究背景

            Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as AMICA1 (Adhesion molecule interacting with CXADR antigen 1), a protein related to the JAM family, is restricted to leukocytes and promotes their adhesion to endothelial cells. It contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail involved in activation signaling. Monocytic JAML/AMICA1 plays a critical role in regulating monocyte transendothelial migration (TEM) probably via binding to the endothelial coxsackie and adenovirus receptor (CAR) and other tight junction-associated adhesive molecules. The Expression of JAML/AMICA1 is restricted to the hematopoietic tissues with the exception of liver. JAML may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, JAML/AMICA1 also enhances myeloid leukemia cell adhesion to endothelial cells.

             JAML/AMICA1 protein 參考資料
          • Moog-Lutz C, et al. (2003) JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood. 102(9): 3371-8.
          • Luissint AC, et al. (2008) JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation. J Cell Biol. 183(6): 1159-73.
          • Guo YL, et al. (2009) Role of junctional adhesion molecule-like protein in mediating monocyte transendothelial migration. Arterioscler Thromb Vasc Biol. 29(1): 75-83.
          • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”