CD18 cDNA Clone: Expression and Clone Vector / Plasmid
CD18 cDNA / Gene Overview
ITGB2 gene / cDNA is a protein-coding gene which located on 21q22.3. The ITGB2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog.195 organisms have orthologs with human gene ITGB2.
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
CD18 cDNA / Gene Sequence
LOCUS NM_000211 2973 bp mRNA linear PRI 12-AUG-2018
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