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Carbonic anhydrase II (Protein | Antibody | cDNA Clone | ELISA Kit)

All Carbonic anhydrase II reagents are produced in house and quality controlled, including 9 Carbonic anhydrase II Antibody, 58 Carbonic anhydrase II Gene, 3 Carbonic anhydrase II IP Kit, 2 Carbonic anhydrase II Protein, 3 Carbonic anhydrase II qPCR. All Carbonic anhydrase II reagents are ready to use.

Carbonic anhydrase II Protein (2)

    Carbonic anhydrase II Antibody (9)

      Carbonic anhydrase II cDNA Clone (58)

      Carbonic anhydrase II Background

      The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase II is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.

      Carbonic anhydrase II References

      • Lehtonen J, et al. (2004) Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family. The Journal of Biological Chemistry. 279: 2719-27.
      • Lindskog S. (1997) Structure and mechanism of carbonic anhydrase. Pharmacology & Therapeutics. 74(1):1-20.
      • Lilias A, et al. (1972) Crystal Structure of Human Carbonic Anhydrase C. Nature new biology. 235: 131-7.
      • Li XJ, et al. (2002) Carbonic Anhydrase II Binds to and Enhances Activity of the Na+/H+ Exchanger. The Journal of Biological Chemistry. 277: 36085-91.

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