C1s cDNA Clone: Expression and Clone Vector / Plasmid

C1s cDNA / Gene Overview

C1s gene / cDNA is a protein-coding gene which located on 12p13.31. The C1S gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.193 organisms have orthologs with human gene C1S.

C1s cDNA / Gene Function

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]

C1s cDNA / Gene Sequence

LOCUS
LOCUS NM_001734 2769 bp mRNA linear PRI 01-JUL-2018
DEFINITION
Homo sapiens complement C1s (C1S), transcript variant 2, mRNA.
ACCESSION
NM_001734
VERSION
NM_001734.4

This sequence information is just for reference only.

C1s Family & Reagents

C1s Gene family reagents (Complement system)

Approved Symbol Reagent list
C1QB
C5
C7
CD59
CFD
CFHR1
CR2
Approved Symbol Reagent list
C2
C6
CD46
CFB
CFH
CFHR2
   

C1s Gene family reagents (Sushi domain containing)

Approved Symbol Reagent list
CFH
CFHR1
IL2RA
APOH
SEZ6L2
CFHR2
PAPPA2
C7
CD55
C6
Approved Symbol Reagent list
SELL
SELE
F13B
HP
CD46
SELP
C2
TPO
SUSD4
CR2

C1s cDNA / Gene Expression

Broad expression in liver (RPKM 683.7), gall bladder (RPKM 363.8) and 18 other tissues