ATG10/Apg10 cDNA Clone: Expression and Clone Vector / Plasmid

ATG10/Apg10 cDNA / Gene Overview

ATG10 cDNA / gene is a gene with protein product which located on 5q14.1-q14.2. The ATG10 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and frog. 226 organisms have orthologs with human gene ATG10.

ATG10/Apg10 cDNA / Gene Function

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]

ATG10/Apg10 cDNA / Gene Sequence

LOCUS
AK024016 1438 bp mRNA linear PRI 09-JAN-2008
DEFINITION
Homo sapiens cDNA FLJ13954 fis, clone Y79AA1001145.
ACCESSION
AK024016
VERSION
AK024016.1

This sequence information is just for reference only.

ATG10/Apg10 Family & Reagents

Gene family

ATG10/Apg10 Gene family reagents (Autophagy related)

Approved Symbol Reagent list
GABARAP
GABARAPL2
MAP1LC3B
Approved Symbol Reagent list
GABARAPL1
MAP1LC3A
   

ATG10/Apg10 cDNA / Gene Alias

  • DKFZP586I0418
  • FLJ13954

ATG10/Apg10 cDNA / Gene Expression

Ubiquitous expression in testis (RPKM 1.1), thyroid (RPKM 0.8) and 25 other tissues