AKT2 Protein

AKT2 Protein Overview

AKT2 reagents

AKT2 encodes a protein belonging to a subfamily of serine/threonine kinases containing Src homology 2 (SH2)-like domains (Cheng et al., 1992).

AKT2 protein family

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

AKT2 protein name

Recommended name
RAC-beta serine/threonine-protein kinase
Alternative name
Protein kinase Akt-2 Protein kinase B beta PKB beta RAC-PK-beta

AKT2 Protein Sequence

Species Human AKT2 protein
Length 481
Mass (Da) 55769
Sequence Human AKT2 protein sequence
Species Mouse AKT2 protein
Length 481
Mass (Da) 55742
Sequence Mouse AKT2 protein sequence
Species Rat AKT2 protein
Length 481
Mass (Da) 55543
Sequence Rat AKT2 protein sequence

AKT2 Protein Molecular Weight & PI

RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-481 RAC-beta serine/threonine-protein kinase.

Molecular weight (Da)

55768.79

Theoretical pI

5.98

AKT2 Protein Structure

Crystal structure of human Akt2 in complex with GSK690693
Deposited
2008-05-01   Released:  2008-10-21
Deposition Author(s)
Concha, N.O., Smallwood, A.
Organism(s)
Homo sapiens
Expression System
Spodoptera frugiperda
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.0000 Å
R-Value Free
0.246
R-Value Work
0.206
3D0E From PDB

Human AKT2 protein Secondary structure

AKT2 Protein Interaction

Recombinant AKT2 Protein Feature

AKT2 Protein, Human, Recombinant (His & GST Tag)

High Purity
> 90 % as determined by SDS-PAGE.
Low Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
High Activity
Kinase activity untested

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