Von Willebrand Factor (Protein | Antibody | cDNA Clone | ELISA Kit)

All Von Willebrand Factor reagents are produced in house and quality controlled, including 6 Von Willebrand Factor Antibody, 2 Von Willebrand Factor ELISA, 1 Von Willebrand Factor Lysate, 1 Von Willebrand Factor Protein. All Von Willebrand Factor reagents are ready to use.

Von Willebrand Factor Protein (1)

Von Willebrand Factor Antibody (6)

Von Willebrand Factor ELISA Kit & Match Antibody ELISA Pair Set ( 2 )

Von Willebrand Factor Lysate (1)

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Von Willebrand Factor Background

Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

Von Willebrand Factor References

  • Sadler JE. (1998) Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem, 67: 395-424.
  • Batlle J, et al. (2009) Von Willebrand factor/factor VIII concentrates in the treatment of von Willebrand disease. Blood Coagul Fibrinolysis. 20(2):89-100.
  • Sadler JE. (2009) von Willebrand factor assembly and secretion. J Thromb Haemost. 7 Suppl 1:24-7.
  • Auton M, et al. (2010) The mechanism of VWF-mediated platelet GPIbalpha binding. Biophys J. 99(4):1192-201.
  • Bowen DJ. (2010) Sugar targets VWF for the chop. Blood. 115(13):2565.
  • Lpez JA, et al. (2010) VWF self-association: more bands for the buck. Blood. 116(19):3693-4.