DR4 (Protein|Antibody|cDNA Clone|ELISA Kit)

All DR4 reagents are produced in house and quality controlled, including 9 DR4 Antibody, 1 DR4 ELISA, 15 DR4 Gene, 3 DR4 Lysate, 3 DR4 Protein, 1 DR4 qPCR. All DR4 reagents are ready to use.

Recombinant DR4 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-human IgG1-Fc & His, C-His.

DR4antibodies are validated with different applications, which are ELISA, FCM, ELISA(Det), ELISA(Cap).

DR4cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each DR4 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

DR4ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

DR4 Protein (3)

Species

DR4 Protein, Human, Recombinant (Fc Tag)

10408-H02H

Expression host: HEK293 Cells

Human TRAIL R1/CD261/TNFRSF10A Protein 8782

DR4 Protein, Human, Recombinant (His Tag)

10408-H08H

Expression host: HEK293 Cells

Human TRAIL R1/CD261/TNFRSF10A Protein 8784

DR4 Protein, Human, Recombinant (His & Fc Tag)

10408-H03H

Expression host: HEK293 Cells

Human TRAIL R1/CD261/TNFRSF10A Protein 8783
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DR4 Antibody (9)

Application Clonality
Host

Anti-DR4 Antibody

10408-T16

Application: ELISA

Clonality: PAb

Anti-DR4 Antibody

10408-R001

Application: ELISA,ELISA(Det)

Clonality: MAb

Anti-DR4 Antibody

10408-MM07

Application: ELISA

Clonality: MAb

Anti-DR4 Antibody

10408-MM01

Application: ELISA(Cap),FCM

Clonality: MAb

Human TRAIL R1/CD261/TNFRSF10A Flow Cytometry (FC) 5010

Anti-DR4 Antibody (FITC)

10408-MM01-F

Application: FCM

Clonality: MAb

Human TRAIL R1/CD261/TNFRSF10A Flow Cytometry (FC) 5008

Anti-DR4 Antibody (PE)

10408-MM01-P

Application: FCM

Clonality: MAb

Human TRAIL R1/CD261/TNFRSF10A Flow Cytometry (FC) 5008

Anti-DR4 Antibody

10408-RP01

Application: ELISA

Clonality: PAb

Anti-DR4 Antibody

10408-RP02

Application: ELISA

Clonality: PAb

Anti-DR4 Antibody

10408-R101

Application: FCM

Clonality: MAb

Human TRAIL R1/CD261/TNFRSF10A Flow Cytometry (FC) 5007
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DR4 ELISA KIT & match antibody elias pair set ( 1 )

DR4 Matched ELISA Antibody Pair Set,Human

SEK10408

Assay Range: 2.34 pg/ml

Human TRAIL R1/CD261/TNFRSF10A ELISA Kit Standard Curve 7061

DR4 cDNA Clone (15)

Human
Rhesus
XM_015144975.1

DR4 qPCR Primer (1)

DR4 Lysate (3)

Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 antigen, is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. TRAIL R1/CD261/TNFRSF10A serves as a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TRAIL R1 can promote the activation of NF-kappa-B. TRAIL R1/CD261/TNFRSF10A induces apoptosis of many transformed cell lines but not of normal tissues, even though its death domain-containing receptor, DR4, is expressed on both cell types.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Protein
Antibody
ELISA
Gene
qPCR
Lysate
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