PIGR (Protein | Antibody | cDNA Clone | ELISA Kit)

All PIGR reagents are produced in house and quality controlled, including 8 PIGR Antibody, 3 PIGR ELISA, 26 PIGR Gene, 2 PIGR Lysate, 2 PIGR Protein, 2 PIGR qPCR. All PIGR reagents are ready to use.

PIGR Protein (2)

PIGR Antibody (8)

PIGR ELISA Kit & Match Antibody ELISA Pair Set (3)

PIGR cDNA Clone (26)

NM_002644.2
NM_011082.2

PIGR Lysate (2)

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PIGR Background

Polymeric immunoglobulin receptor, also known asPIGR, is a member of the immunoglobulin superfamilyand aFc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion ofIgAandIgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.

PIGR References

  • Coyne, R. S. et al., 1995, J. Biol. Chem. 269 (50) :31620-31625. 
  • Kaetzel,C.S., 2001,  Curr Biol. 11(1): R35-38.