Anti-Oct4 Antibody

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Anti-Oct4 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Oct4 Antibody
Validated applications
IHC-P
Species reactivity
Reacts with: Mouse
Predicted to React with: Human (Species predicted to react based on 100% sequence homology)
Specificity
Mouse Oct4
Immunogen
A synthetic peptide corresponding to the N-terminus of the Mouse Oct4 / POU5F1
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Mouse Oct4 / POU5F1, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Oct4 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
IHC-P 1:1000-1:4000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Oct4 Antibody (Rabbit Polyclonal antibody) Images

Immunochemical staining of mouse Pou5f1 in mouse skeletal muscle with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Immunochemical staining of mouse Pou5f1 in mouse brain with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Anti-Oct4 Antibody: Alternative Names

Anti-42280 Antibody; Anti-42281 Antibody; Anti-NF-A3 Antibody; Anti-Oct-3/4 Antibody; Anti-Oct3/4 Antibody; Anti-Otf-3 Antibody; Anti-Otf-4 Antibody; Anti-Otf3 Antibody; Anti-Otf3-rs7 Antibody; Anti-Otf3g Antibody; Anti-Otf4 Antibody

Oct4 Background Information

The POU5F1 gene, which encodes the POU domain, class 5, transcription factor 1 (also known as Oct-4), is expressed in embryonic stem cells where it regulates pluripotency and proliferation.The POU5F1 gene encodes one of the "core" transcription factors necessary to establish and maintain pluripotency in mammals. Its function depends on its precise level of expression, so its transcription has to be tightly regulated. POU5F1 is a key regulator of self-renewal and differentiation in embryonic stem cells and may be associated with initiation, promotion, and progression in cancer. POU5F1 is a transcription factor and master regulator of cell pluripotency with indispensable roles in early embryo development and cell lineage specification. The role of embryonic POU5F1 in blastocyst formation and cell lineage specification differs between mammalian species .
Full Name
POU class 5 homeobox 1
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