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NAALADL1 Antibody, Rabbit PAb, Antigen Affinity Purified

產品資料評論相關產品實驗方法
Mouse NAALADL1 抗體產品資訊
免疫原:Recombinant Mouse NAALADL1 protein (Catalog#50937-M07H)
Clone ID:
Ig類型:Rabbit IgG
濃度:
內毒素:
緩衝液:0.2 μm filtered solution in PBS with 5% trehalose
抗體製備方法:Produced in rabbits immunized with purified, recombinant Mouse NAALADL1 (rM NAALADL1; Catalog#50937-M07H; Q7M758; Pro29-Leu745). NAALADL1 specific IgG was purified by Mouse NAALADL1 affinity chromatography.
Mouse NAALADL1 抗體使用指導
特異性:Mouse NAALADL1
推薦應用:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse NAALADL1 . The detection limit for Mouse NAALADL1 is 0.00975 ng/well.

IHC-P: 0.1-2 μg/mL

儲存方法:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse NAALADL1 Antibody IHC Application Image
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Caption:
Immunochemical staining of mouse NAALADL1 in mouse brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
NAALADL1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Other NAALADL1 Antibody Products
NAALADL1 研究背景

N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.

Mouse NAALADL1 參考資料
  • Stauch BL. 1989, Neurosci Lett. 100 (1-3): 295-300.
  • Shneider BL. et al., 1997, J. Biol. Chem. 272: 31006-15.
  • Pangalos MN. et al., 1999, J. Biol. Chem. 274: 8470-83.
  • Thomas AG. et al., 1999, Brain Res. 843 (1-2): 48-52.
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    Size / Price
    貨號: 50937-RP02-50
    目錄價:   (Save )
    單價:      [How to order]
    庫存In Stock
     運輸說明
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”