TNFR2 ELISA Kit, Mouse

Cat: KIT50128

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TNFR2 ELISA Kit, Mouse General Information
Product name
TNFR2 ELISA Kit, Mouse
Assay type
Solid Phase Sandwich ELISA (quantitative)
Detection antibody conjugate
Sample type
4.1 pg/mL
Assay range
6.25-400 pg/mL
Recognizes both recombinant and natural Mouse TNFR2
  Intra-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 0.07 0.15 0.29
SD 0.00 0.00 0.01
CV(%) 4.4% 2.7% 1.7%
  Inter-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 0.08 0.16 0.32
SD 0.00 0.01 0.03
CV(%) 5.3% 5.9% 7.8%
The recovery of Mouse TNFRSF1B spiked to different levels throughout the range of the assay in related matrices was evaluated.
Sample Average % Recovery Range
serum (n=3) 76.69545745361481 75-78%
  Recovery of detected
1:2 83%
1:4 121%
1:8 114%
1:16 80%
  Recovery of detected
1:2 85%
1:4 79%
1:8 80%
1:16 77%
Materials provided
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
Product overview
This TNFR2 ELISA Kit, Mouse is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse TNFR2 protein in Serum . It contains recombinant Mouse TNFR2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
This ELISA Kit is shipped at ambient temperature.
Unopened Kit: Store at 2 - 8℃
Opened/Reconstituted Reagents: Please refer to CoA
TNFR2 ELISA Kit, Mouse Images
Mouse TNFR2/TNFRSF1B/CD120b ELISA Kit Standard Curve 126
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Mouse TNFR2/TNFRSF1B/CD120b ELISA Kit Specificity 167
This assay recognizes both recombinant and natural mouse TNFRSF1B. The factors listed above were prepared at 50 ng/mL in dilution buffer and assayed for cross-reactivity and interference. No cross-reactivity or interference was observed.
TNFR2 ELISA Kit, Mouse Alternative Names
CD120b ELISA Kit, Mouse;p75 ELISA Kit, Mouse;TNF-alphaR2 ELISA Kit, Mouse;TNF-R-II ELISA Kit, Mouse;TNF-R2 ELISA Kit, Mouse;TNF-R75 ELISA Kit, Mouse;TNFalpha-R2 ELISA Kit, Mouse;TNFBR ELISA Kit, Mouse;Tnfr-1 ELISA Kit, Mouse;Tnfr2 ELISA Kit, Mouse;TNFR80 ELISA Kit, Mouse;TNFRII ELISA Kit, Mouse
TNFR2 Background Information

Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2/CD120b/TNFRSF1B is not a major contributing factor to the genetic risk of type 2 diabetes, its associated peripheral neuropathy and hypertension and related metabolic traits in North Indians. Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B) has been reported to be associated with SLE risk in Japanese populations. TNFR2/CD120b/TNFRSF1B serves as a receptor with high affinity for TNFSF2 and approximately 5-fold lower affinity for homotrimeric TNFSF1. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
tumor necrosis factor receptor superfamily, member 1b
  • Komata T, et al. (1999) Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus. Tissue Antigens. 53(6): 527-33.
  • Tsuchiya N, et al. (2001) Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test. Genes Immun. 2(6): 317-22.
  • Guo G, et al. (1999) Role of TNFR1 and TNFR2 receptors in tubulointerstitial fibrosis of obstructive nephropathy. Am J Physiol. 277(5): 766-72.
  • Product Description Assay Range (pg/ml) Sample Type Catalog# (PDF)
    TNFR2 Matched ELISA Antibody Pair Set,Mouse 9.4 pg/ml SEK50128
    info info
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